While most of the buzz around green coffee bean extract (GCBE) has revolved around its use as a weight loss supplement, there is promising evidence that it may help in the control and treatment of several other medical conditions, most notably, high blood pressure.
Could GCBE be the next great thing in the battle against high blood pressure? Study results are very promising.
In 2002, one study noted that chlorogenic acid, a key component of green coffee bean extract, reduced spontaneous high blood pressure in lab rats,
A subsequent study was conducted on human subjects. In 2004, 117 mildly-hypertensive men participated in a controlled, double-blind study to test the effectiveness of 3 different doses of green coffee bean extract on their blood pressure. After 28 days, the men taking 93mg or 185 mg of GCBE had significant reductions in both systolic and diastolic blood pressure as compared to the men given a placebo.
(Read the full text pdf of this study , published by the Japanese Society of Hypertension)
A smaller 2006 study, this time using purified chlorogenic acid derived from green coffee beans, yielded similar results.
Green cofee beans contain the same powerful polyphenol antioxidants as are found in green tea, most notably, a group called chlorogenic acids (CGA) - which is considered to be the key component of GCBE. In general, antioxidants fight the negative effects of free radicals which damage cells and contribute to aging and disease.
A 2006 German lab study examined the effects of bread enriched with green coffee extract and evaluated it's effect on human cells in culture. The study attempted to demonstrate GCBE's ability to protect healthy tissue from toxins and to guard against the kind of chemicals which damage a cell's DNA, causing mutations or even cancer. Results were evaluated against a standardized scale antioxidant capacity. The conclusion: cells treated with the supplemented bread showed increased resistance of colon and liver cells to oxidative stress.
It's important to understand that findings from "in vitro" studies like this often don't hold up in clinical studies on humans. Further study is needed to determine if green coffee bean extract is effective in real-life situations and to establish dosing and safety guidelines, but it certainly is fascinating research which could someday become a tool in preventing and treating cancer.
While there are some claims that GCBE can help prevent diabetes, there are no clinical studies to support that claim. There are some studies on the consumption of ordinary coffee, but evidence to back up these statements is weak at best.
There are no studies or any other evidence to substantiate this claim. This is pure speculation based upon some studies done on coffee drinkers, who consumed regular roasted coffee.